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Nov112013

Sleep and The Brain’s Amazing Detox System  

To function well our brain needs the right conditions. Its needs adequate nutrients and it needs to get rid of the waste products of metabolism and other molecules that build up in the brain which are know to be associated with neurodegeneration.  Until recently scientists have not really known how the brain gets rid of toxins and metabolic by-products.  However, in recent years scientists at the University of Rochester Medical Centre have made a huge breakthrough in discovering a  system that rapidly  flushes waste from the brain [1]. This “plumbing” system is called the glymphatic system.  It pumps the cerebrospinal fluid (CSF) through brain tissue and directs it to drain back into the circulatory system so that it can clear the brain of  molecules that disrupt the brains environment and which are associated with neurodegeneration.

Previously I posted a link to an article that speculated that Cranial Osteopathic treatment, which targets improved CSF circulation, might help the glymphatic system to function.

Now there is firm evidence that links sleep to the brains glymphatic system.  According to a new study published in Science [2], during sleep the glympahtic system becomes highly active in its ‘cleaning process’ and literally clears away the toxins responsible for Alzheimer’s disease and other neurological disorders.

Scientists believe that the detoxification and cleaning process carried out by the glymphatic system is difficult for the brain to perform when we are awake given the many other complex tasks it needs to perform and that its only when we are asleep that this detox process can be carried out adequately.  Also during sleep brain cells can ‘shrink’ up to 60%  and this creates the extra space needed for cerebral spinal fluid (CSF) to wash freely through the brain tissue.

I remember once having my sleep deprived  head -fog completely cleared with Cranial Osteopathy. Caring for a sick young baby for several days and nights meant I hardly slept  and as a result I felt absolutely terrible. I had to work but could hardly think.  A fellow Osteopath spent 15 minutes getting my cranial mechanism working and I remember being totally amazed at the realization that at the end of the treatment I felt completely normal, as if I’d just slept 8 hours. I now wonder if the explanation for this little miracle was that the Osteopathic treatment somehow got my  glymphatic system working.

Also a little reminder of the talk Im giving next week at the Mindd Foundation.  Join me and the Mindd Foundation for this seminar on sleep, breathing and digestive function at the Mindd Centre, Edgecliff, Thursday November 21, 6:30pm - 8:30pm. To learn more and to book tickets please visit the link .

 

REFERENCES

1.            Iliff, J., et al., A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid Sci. Transl. Med. , 2012. 4(147 ra111).

2.            Xie, A. and E. al, Sleep initiated fluid flux drives metabolite clearance from the adult brain. Science, 2013.

 

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